Status:
COMPLETED
Letrozole vs Danazol for Endometriosis-Related Pain: Randomized Trial
Lead Sponsor:
Sidra Salman
Conditions:
Endometriosis
Eligibility:
FEMALE
18-45 years
Phase:
PHASE2
Brief Summary
Background: Endometriosis is a chronic gynecological condition defined by the ectopic presence of endometrial glands and stroma outside the uterine cavity, most commonly diagnosed via laparoscopy. Wh...
Detailed Description
Introduction: Endometriosis is defined by the ectopic presence of functional endometrial glands and stroma outside the uterine cavity, most commonly diagnosed via direct laparoscopic visualization (1...
Eligibility Criteria
Inclusion
- Women aged 18-45 years
- Surgically or clinically diagnosed endometriosis
- Moderate to severe pelvic pain (NRS ≥ 4 for at least 3 months)
- Willing to use effective contraception during the study
- Able to provide informed consent
Exclusion
- Pregnant or breastfeeding
- Severe hepatic disease, thromboembolic disorder, or contraindication to study drugs
- Use of hormonal therapy within the last 8 weeks
- Known hypersensitivity to Letrozole or Danazol
- Participation in another clinical trial within the last 3 months
Key Trial Info
Start Date :
April 10 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07183787
Start Date
April 10 2019
End Date
July 31 2025
Last Update
September 19 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Sharif Medical and Dental College
Lahore, Punjab Province, Pakistan, 54700