Status:
NOT_YET_RECRUITING
Clinical, Radiological, Tissue and Biological Phenotyping for the Analysis of the Transition From Physiology to Pathology in Pulmonary Diseases With Pulmonary Hypertension
Lead Sponsor:
Assistance Publique Hopitaux De Marseille
Conditions:
Pulmonary Hypertension
Chronic Pulmonary Disease
Eligibility:
All Genders
18+ years
Brief Summary
This is a monocentric, case-control, comparative study aiming at investigating the transition from physiological to pathological pulmonary circulation in patients with pulmonary hypertension (PH) and ...
Eligibility Criteria
Inclusion
- Male or female over 18 years of age
- Patient who has received information about the study and has not expressed any objection
- Patient who is a beneficiary or entitled person under a social security scheme
- Patient requiring thoracic surgery for an acute or chronic acquired pathology with planned resection of lung parenchyma.
- Group A: patients on the lung transplant list with chronic lung disease and pulmonary hypertension\*.
- Group B: control patients with chronic lung disease without pulmonary hypertension on the lung transplant list or with an indication for lung resection surgery for diagnostic or therapeutic purposes.
- Group C: control patients without chronic lung disease or pulmonary hypertension with an indication for lung resection.
- \*Pulmonary hypertension is defined by a mean resting pulmonary arterial pressure of 20 mmHg and pulmonary vascular resistances \> 2UW and an occlusion pulmonary arterial pressure ≤ 15 mmHg.
Exclusion
- Person in exclusion period from another research protocol at the time the no-objection is collected
- Subjects covered by articles L1121-5 to 1121-8 of the French Public Health Code (minors, adults under guardianship or trusteeship, patients deprived of their liberty, pregnant or breast-feeding women).
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2027
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT07184671
Start Date
September 1 2025
End Date
September 1 2027
Last Update
September 22 2025
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