Status:
ACTIVE_NOT_RECRUITING
Mechanistic Study of SPARC-Mediated Regulation of Neutrophil Extracellular Trap Formation in the Brain Metastatic Microenvironment of Breast Cancer
Lead Sponsor:
Second Xiangya Hospital of Central South University
Conditions:
Neuro-Oncology
MRI Imaging
Eligibility:
All Genders
18-80 years
Brief Summary
The objective of this observational study is to investigate the characteristics of the tumor microenvironment in patients with brain tumors using multi-modal magnetic resonance imaging (MRI). The prim...
Eligibility Criteria
Inclusion
- conventional MRI revealed intracranial space-occupying lesions and suspected high-grade gliomas, brain metastases and meningiomas；
- It is planned to perform a brain tumor resection surgery in this institution.
Exclusion
- other CNS diseases in addition to brain tumors;
- pathologically confirmed brain tumors not belonging to any of the three selected types;
- contraindications to the use of gadolinium contrast, including hypersensitivity to contrast agents, renal dysfunction, pregnancy or lactation;
- contraindications to MRI;
- poor image quality unsuitable for subsequent analyses;
- age younger than 18 years.
Key Trial Info
Start Date :
January 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2030
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT07185646
Start Date
January 1 2023
End Date
December 30 2030
Last Update
September 23 2025
Active Locations (1)
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1
the Second Xiangya Hospital of Central South University
Changsha, Hunan, China, 410011