Status:
RECRUITING
Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas
Lead Sponsor:
National Health Research Institutes, Taiwan
Conditions:
Late-Life Adults
Late-Life Prodromal Depression
Eligibility:
All Genders
55+ years
Phase:
NA
Brief Summary
This randomized controlled trial will examine the effects of mindfulness-based interventions and brain stimulation interventions on cognitive function and psychological well-being in older adults. The...
Eligibility Criteria
Inclusion
- Inclusion Criteria for individuals participating in mindfulness-based Interventions:
- Literate or have received an education above the elementary level.
- Have normal or corrected vision and hearing, able to communicate and understand explanations.
- Right-handed individuals as assessed by the Edinburgh Handedness Inventory.
- Exclusion Criteria for individuals participating in mindfulness-based Interventions:
- Individuals with dementia, stroke, cerebrovascular disease, brain injury, epilepsy, or Parkinson's disease.
- Individuals with neurological system disorders.
- Individuals with alcohol or drug dependence.
- Individuals with other major physical illnesses, such as diabetes, heart failure, or endocrine abnormalities, or those who have experienced an acute myocardial infarction within the past three months.
- Individuals with metal objects in the body that cannot undergo magnetic resonance imaging (MRI), such as cardiac pacemakers, vascular clips, hearing aids, artificial joints, steel pins, etc.
- Individuals with Claustrophobia.
- Individuals in pregnancy or possibility of pregnancy.
- Inclusion Criteria for individuals participating in brain stimulation Intervention:
- Individuals diagnosed with major depressive disorder by psychiatrists according to the Diagnostic and Statistical Manual, and who can cooperate with the psychiatric outpatient clinic regulations.
- Literate or have received an education above the elementary level.
- Have normal or corrected vision and hearing, able to communicate and understand explanations.
- Right-handed individuals as assessed by the Edinburgh Handedness Inventory.
- Individuals are prescribed brain stimulation therapy by clinical physicians.
- Exclusion Criteria for individuals participating in brain stimulation Intervention:
- Individuals with dementia, stroke, cerebrovascular disease, brain injury, epilepsy, or Parkinson's disease.
- Individuals with neurological system disorders.
- Individuals with alcohol or drug dependence.
- Individuals with other major physical illnesses, such as diabetes, heart failure, or endocrine abnormalities, or those who have experienced an acute myocardial infarction within the past three months.
- Individuals with metal objects in the body that cannot undergo magnetic resonance imaging (MRI), such as cardiac pacemakers, vascular clips, hearing aids, artificial joints, steel pins, etc.
- Individuals with Claustrophobia.
- Individuals in pregnancy or possibility of pregnancy.
Exclusion
Key Trial Info
Start Date :
August 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2028
Estimated Enrollment :
124 Patients enrolled
Trial Details
Trial ID
NCT07186023
Start Date
August 1 2025
End Date
December 1 2028
Last Update
September 22 2025
Active Locations (2)
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1
Shuang Ho Biomedical Park, Taipei Medical University
New Taipei City, Taiwan, 235603
2
National Center for Geriatrics and Welfare Research
Yunlin, Taiwan, 632007