Status:
RECRUITING
A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance
Lead Sponsor:
AbbVie
Conditions:
Mid Face Volume Deficit
Eligibility:
All Genders
22-65 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to evaluate the safety and effectiveness of JUVÉDERM products in adults seeking improvement in facial volume and/or skin quality.
Eligibility Criteria
Inclusion
- Must meet at least 3 of the following criteria for treatment in the face with at least 2 JUVÉDERM products, per investigator's assessment:
- Minimal, moderate, or severe on Allergan Temple Hollowing Scale (ATHS)
- Moderate or severe for both eyes on Allergan Infraorbital Hollow Scale (AIHS)
- Moderate or severe on Allergan Cheek Smoothness Scale (ACSS)
- Moderate, significant, or severe on Mid-face Volume Deficit Scale (MFVDS)
- Moderate or severe on Nasolabial Fold Severity Scale (NLFSS)
- Minimal, mild, or moderate on Allergan Lip Fullness Scale 2 (ALFS2)
- Moderate or severe on Allergan Chin Retrusion Scale (ACRS)
- Moderate or severe on Allergan Loss of Jawline Definition Scale (ALJDS)
- Must be in good health as determined by subject's medical history, physical examination, and vital sign measurements.
Exclusion
- Prior treatment with non-permanent soft tissue fillers or fat-reducing injectables in the face or neck within 12 months prior to screening.
- Excessively loose skin in the face and/or neck.
- Tendency to develop hypertrophic scarring and/or keloid scarring.
Key Trial Info
Start Date :
September 25 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2026
Estimated Enrollment :
94 Patients enrolled
Trial Details
Trial ID
NCT07186595
Start Date
September 25 2025
End Date
August 1 2026
Last Update
December 22 2025
Active Locations (10)
Enter a location and click search to find clinical trials sorted by distance.
1
Kian Aesthetic Institute /ID# 277045
Los Angeles, California, United States, 90025
2
West Dermatology La Jolla /ID# 277034
San Diego, California, United States, 92121
3
Pacific Clinical Innovations /ID# 277026
Vista, California, United States, 92083
4
Skin Research Institute LLC /ID# 277038
Coral Gables, Florida, United States, 33146-1837