Status:
COMPLETED
Specific Dietary Fibers May Enhance Colonic Adaptation in Short Bowel Syndrome Through Microbial and Metabolic Mechanisms That Drive Functional Compensation.
Lead Sponsor:
Jinling Hospital, China
Conditions:
Short Bowel Syndrome
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Ten patients with short intestines in clinical practice were intervened with dietary fiber. Serum and feces before and after the dietary fiber intervention were collected, and relevant indicators of n...
Eligibility Criteria
Inclusion
- All participants in Cohort 1 were recruited at the Eastern Theatre Command General Hospital (Nanjing, China) and provided written informed consent. The primary inclusion criterion was a confirmed diagnosis of type II or type III short bowel syndrome in patients aged 18
- 70 years. Participants were excluded if they had other gastrointestinal diseases, malignant tumours, autoimmune diseases, infectious diseases or renal insufficiency (severe kidney disease with creatinine levels exceeding 3.0 mg/dL), or if they had taken antibiotics for more than three days within the preceding three months.
Exclusion
Key Trial Info
Start Date :
February 5 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 15 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT07186608
Start Date
February 5 2025
End Date
August 15 2025
Last Update
September 22 2025
Active Locations (1)
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1
Eastern Theater Command General Hospital
Nanjing, China