Status:

COMPLETED

The Incidence of Early Trauma Induced Coagulopathy and Hyperfibrinolysis in Severely Injured Trauma Patients in the Emergency Room: a Retrospective Cohort Study

Lead Sponsor:

Medical University of Graz

Conditions:

Early Trauma Induced Coagulopathy

Tic

Eligibility:

All Genders

18+ years

Brief Summary

The aim of this study is to quantify the incidence of eTIC (defined as an elevated appt) and hyperfibrinolysis (defined as Ly30\>7) in early trauma patients. To identify patients at risk of eTIC and h...

Detailed Description

Despite excessive efforts to reduce the number of preventable deaths in patients suffering from traumatic injuries, hemorrhage is still a leading cause of morbidity and mortality in this patient group...

Eligibility Criteria

Inclusion

  • Age \< 18 years
  • Sever trauma (ISS\>16)
  • Coagulation parameters (PT, aPTT, INR, fibrinogen, TEG) available within the first hour of admission

Exclusion

  • Patients with known pre-existing coagulopathies
  • Patients on anticoagulant therapy prior to trauma
  • Incomplete or missing coagulation data

Key Trial Info

Start Date :

May 25 2025

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 20 2025

Estimated Enrollment :

263 Patients enrolled

Trial Details

Trial ID

NCT07186712

Start Date

May 25 2025

End Date

October 20 2025

Last Update

December 10 2025

Active Locations (1)

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1

Medical University of Graz

Graz, Austria, 8043

The Incidence of Early Trauma Induced Coagulopathy and Hyperfibrinolysis in Severely Injured Trauma Patients in the Emergency Room: a Retrospective Cohort Study | DecenTrialz