Status:

NOT_YET_RECRUITING

Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications

Lead Sponsor:

University General Hospital of Patras

Conditions:

Postoperative Pulmonary Atelectasis

Postoperative Pulmonary Complications

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Dri...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • \>17 years old
  • Surgery with general anesthesia \& invasive mechanical ventilation
  • Preoperative ARISCAT score estimation \>25
  • Exclusion Criteria:
  • \<18 years old
  • Preoperative ARISCAT score estimation \<26
  • Women during pregnancy or just given birth
  • Other type of anesthesia (Not general)
  • Contraindication of administration of neuromuscular blockade agents.
  • Contraindication of cease of spontaneous ventilation.
  • Mechanical ventilation without endotracheal intubation.
  • Severe heart failure / Severe cardiac arrhythmia.
  • Severe emphysematous lung disease.
  • Patient denial of participation in the trial.

Exclusion

    Key Trial Info

    Start Date :

    October 1 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    November 30 2027

    Estimated Enrollment :

    200 Patients enrolled

    Trial Details

    Trial ID

    NCT07186933

    Start Date

    October 1 2025

    End Date

    November 30 2027

    Last Update

    September 22 2025

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