Status:
RECRUITING
Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.
Lead Sponsor:
Nova Southeastern University
Conditions:
Amyotrophic Lateral Sclerosis (ALS)
Primary Lateral Sclerosis (PLS)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to evaluate the impact of non-invasive electrical stimulation, when placed on the facial muscles can reduce facial pain and improve jaw mobility, and chewing in indi...
Detailed Description
In this prospective, cross-sectional study, individuals with ALS and PLS will participate in one in-person clinic visit, followed by a telephone interview 24 hours post-treatment. During the clinic vi...
Eligibility Criteria
Inclusion
- Diagnosis of possible, probable, or definite ALS (El-Escorial Revisited) OR diagnosis of definite PLS by the treating neurologist and based on the consensus diagnostic criteria for PLS
- Subjective report of jaw pain, indicated by a NRS score of \> or = 3/10.
Exclusion
- history of head or neck cancer
- history of CVA
- history of past facial surgery with hardware placement
- history of pacemaker
- diagnosis of significant cognitive impairment by the treating physician
- history of seizures or diagnosis of epilepsy
- open wound at the area of electrode placement
- complete loss of sensation at the area of electrode placement
Key Trial Info
Start Date :
January 30 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 13 2026
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT07187388
Start Date
January 30 2026
End Date
August 13 2026
Last Update
December 4 2025
Active Locations (1)
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1
Nova Southeastern University, David and Cathy Husman Neuroscience Institute
Davie, Florida, United States, 33314