Status:
RECRUITING
Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)
Lead Sponsor:
Hospital Moinhos de Vento
Collaborating Sponsors:
Federal University of Health Science of Porto Alegre
Conditions:
Mechanical Ventilation
Critical Illness
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This clinical study aims to compare the effects of conventional physical therapy alone versus conventional physical therapy combined with neuromuscular electrical stimulation (NMES) in patients admitt...
Detailed Description
This randomized clinical trial will investigate the effects of neuromuscular electrical stimulation (NMES) in critically ill patients undergoing invasive mechanical ventilation. Participants will be r...
Eligibility Criteria
Inclusion
- Patients will be eligible if they are 18 years or older, are under invasive mechanical ventilation (IMV), and are expected to require IMV for more than 48 hours.
Exclusion
- Body mass index (BMI) greater than or equal to 35 kg/m²;
- Length of ICU stay longer than 7 ICU-free days or more than 3 continuous days of invasive mechanical ventilation (IMV) before enrollment;
- Known intracranial process (e.g., stroke, intracranial hypertension);
- Neuromuscular disease (e.g., Guillain-Barré syndrome, myasthenia gravis) at ICU admission;
- Inability to speak Portuguese or pre-existing cognitive impairment prior to ICU admission;
- Any condition that prevents neuromuscular electrical stimulation (NMES) treatment or assessment of the primary outcome in both legs (e.g., skin lesions, fractures, or amputation);
- Inability to transfer independently from bed to chair before ICU admission;
- Cardiac arrest as the cause of ICU admission or cardiac arrest before screening;
- Deep vein thrombosis (DVT) or pulmonary embolism (PE) treated for less than 48 hours;
- Pregnant patients;
- Known or suspected malignancy in the legs;
- Any care limitation including a do-not-resuscitate order.
Key Trial Info
Start Date :
September 4 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2027
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07188350
Start Date
September 4 2025
End Date
March 1 2027
Last Update
September 23 2025
Active Locations (1)
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1
Hospital Moinhos de Vento
Porto Alegre, Rio Grande do Sul, Brazil, 90035-902