Status:
RECRUITING
Mitigating the Disinhibiting Effects of Alcohol With Transcranial Magnetic Stimulation
Lead Sponsor:
Michael J. Wesley, PhD
Conditions:
Alcohol Risk Behaviors
Eligibility:
All Genders
21-29 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn how a specific type of brain stimulation affects alcohol-related decision-making and self-control in adults who drink alcohol. The main questions the study ...
Detailed Description
This study aims to understand how brain stimulation affects decision-making and behavioral control after alcohol consumption. Many harmful events related to alcohol use are the result of impaired deci...
Eligibility Criteria
Inclusion
- Age 21-29
- Must be competent in English
- BMI between 19 and 26
- At least a high school education
- Moderate alcohol users (e.g., at least occasional alcohol use, without meeting criteria for alcohol use disorder)
- Negative urine drug screen for illicit drugs
- Negative urine pregnancy test (if applicable) on testing days
Exclusion
- History of seizures or a first-degree relative with seizure history
- History of head trauma or other CNS injuries
- Current or past psychiatric disorders (including substance use disorder, except nicotine or caffeine)
- Contraindications for non-invasive brain stimulation (e.g., metal implants, pacemaker)
- Currently pregnant or breastfeeding
- Current use of medications that lower seizure threshold
- Positive alcohol withdrawal symptoms
- Smokes more than five cigarettes per day (to avoid acute nicotine effects or withdrawal during visits)
Key Trial Info
Start Date :
October 30 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT07188376
Start Date
October 30 2025
End Date
December 1 2026
Last Update
November 5 2025
Active Locations (1)
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1
University of Kentucky
Lexington, Kentucky, United States, 40507