Status:
COMPLETED
Observational Study on GER in Patients With Simple Obesity
Lead Sponsor:
Jing Ma
Conditions:
Obesity &Amp;Amp; Overweight
Gastric Emptying Time
Eligibility:
All Genders
18-65 years
Brief Summary
Dear Patients, The investigators invite participants to take part in an observational study on gastric emptying rate in individuals with simple obesity. This study has been reviewed and approved by th...
Eligibility Criteria
Inclusion
- Diagnostic criteria for obesity (BMI ≥ 28 kg/m²) and/or waist circumference ≥ 90 cm in adult males, ≥ 85 cm in adult females, or waist-to-hip ratio ≥ 0.9 in males and ≥ 0.85 in females;
- Age 18-65 years;
- Consent to undergo venous blood sampling, gastric emptying scintigraphy, and MRI examination with no contraindications to these procedures;
- Consent to participate in this research project.
Exclusion
- Diagnosed with secondary obesity, such as hypothyroidism, Cushing's syndrome, polycystic ovary syndrome, etc.;
- Severe cardiovascular or cerebrovascular disease, rheumatic or immune-mediated disorders;
- Severe metabolic disorders, such as diabetic ketoacidosis, hyperosmolar hyperglycaemic state, etc.;
- Advanced malignant tumours;
- History of medication known to affect glucose/lipid metabolism or gastric emptying rate, such as GLP-1 receptor agonists, glucocorticoids, antibiotics, anxiolytics or antidepressants;
- Pregnancy or lactation;
- Severe bleeding tendency or inability to undergo venous blood sampling;
- Contraindications for gastric emptying scintigraphy, including pregnancy, lactation, severe gastrointestinal disorders such as acute gastrointestinal haemorrhage, intestinal obstruction or perforation, or allergy to components of the test meal;
- Individuals with contraindications for MRI;
- Patients refusing gastric emptying scintigraphy, MRI examination, or refusal to sign the informed consent form;
- Other circumstances deemed unsuitable for the study by the investigator.
Key Trial Info
Start Date :
June 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 30 2025
Estimated Enrollment :
163 Patients enrolled
Trial Details
Trial ID
NCT07188571
Start Date
June 1 2025
End Date
July 30 2025
Last Update
September 23 2025
Active Locations (1)
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1
Ren Ji Hospital
Shanghai, Pudong New Area, China