Status:
NOT_YET_RECRUITING
A Prospective, Randomized, Double-blind Study on the Effects of Different Anesthesia Strategies on Postoperative Cough in Patients Undergoing Video-assisted Thoracoscopic Surgery.
Lead Sponsor:
Fujian Medical University Union Hospital
Conditions:
Chronic Cough
Video-assisted Thoracoscopic Surgery (VATS)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aims to systematically evaluate the effects of different anesthesia methods on postoperative chronic cough in lung cancer patients undergoing video-assisted thoracoscopic lung resection (VA...
Detailed Description
This study is a single-center, prospective, randomized, double-blind controlled study, aiming to explore the effects of different airway management strategies during surgery on the postoperative chron...
Eligibility Criteria
Inclusion
- planned wedge resection, segmentectomy or lobectomy;
- more than 18 years old;
- American Society of Anesthesiologists (ASA) grade ≤Ⅲ;
- body mass index (BMI) ≤24 kg/m2;
- Normal pulmonary function, predicted forced expiratory volume in 1 second (FEV1%) \>50%, resting blood gas analysis showed arterial partial pressure of oxygen (PaO2) ≥75 mmHg and arterial partial pressure of carbon dioxide (PaCO2) \<45 MMHG;
- Normal cardiac function with ejection fraction (EF) \> 50% of predicted value;
- Informed consent and signed informed consent form.
Exclusion
- (1) patients who refuse surgery and/or anesthesia; (2) preoperative pulmonary infection; (3) previous history of ipsilateral surgery or other medical history that may cause extensive pleural adhesions; (4) phrenic nerve palsy on the non-operative side; (5) patients with high risk of preoperative reflux (fasting \<6 hours) or gastroesophageal reflux disease; (6) patients with heart, kidney, liver and other organ dysfunction and surgical contraindications; (7) with severe cognitive, psychological and communication disorders.
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
228 Patients enrolled
Trial Details
Trial ID
NCT07190664
Start Date
October 1 2025
End Date
December 30 2025
Last Update
September 24 2025
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.