Status:
RECRUITING
Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy
Lead Sponsor:
University of Michigan
Conditions:
Posterior Cortical Atrophy
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
This study is being completed to learn if high-definition transcranial direct current stimulation (HD-tDCS) has an effect on visual and thinking abilities in persons with posterior cortical atrophy (P...
Eligibility Criteria
Inclusion
- Diagnosis or symptoms consistent with PCA
- Fluent in English
- HD-tDCS compatible
- Stable on relevant medications for at least approximately 4 weeks prior to study enrollment
- If completing any additional, optional, long-term study visits in a remote location (i.e., not our office), a study partner is required in order to administer HD-tDCS. Those choosing to return to our office may have, but are not required to have, a study partner.
Exclusion
- Other relevant neurological disease (e.g., epilepsy) or injuries (e.g., large vessel stroke, moderate-severe traumatic brain injury) viewed as primary to deficits since these could interfere with etiologic considerations and confound study results
- Active, relevant psychiatric conditions (e.g., bipolar disorder, schizophrenia) since the symptoms of these conditions may confound study participation.
- A recent (e.g., within the past 2 years) significant history of, or current, alcohol or drug abuse/dependence. Remote history of abuse/dependence is not exclusionary as long as it is not considered to be the primary etiology for visuospatial deficits.
- Women that are lactating/breastfeeding, pregnant, or may potentially be pregnant will be excluded from the study.
Key Trial Info
Start Date :
November 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2029
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT07191327
Start Date
November 1 2025
End Date
September 1 2029
Last Update
October 8 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Michigan
Ann Arbor, Michigan, United States, 48109