Status:
NOT_YET_RECRUITING
The Effect of BIPAP on Diaphragmatic Function
Lead Sponsor:
Istanbul Demiroglu Bilim University
Collaborating Sponsors:
Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital
Conditions:
BIPAP Biphasic Intermittent Positive Airway Pressure
Diaphragm Issues
Eligibility:
All Genders
40-80 years
Brief Summary
This research is designed to evaluate how long-term treatment with Bilevel Positive Airway Pressure (BiPAP) influences diaphragm function in patients with Chronic Obstructive Pulmonary Disease (COPD) ...
Detailed Description
Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory condition frequently complicated by chronic hypercapnic respiratory failure. In this population, long-term non-invasive ventil...
Eligibility Criteria
Inclusion
- Being between 40-80 years of age,
- Having a diagnosis of stable COPD for at least 1 year,
- Being in a stable phase (no acute exacerbation within the last 4 weeks),
- Meeting the GOLD 2025 A-B-E classification according to symptoms and exacerbation history,
- Having been initiated on BiPAP therapy with a clinical indication,
- Being willing to participate in the study and providing informed consent.
Exclusion
- Pregnancy,
- Diaphragmatic paralysis,
- Neuromuscular and neurological diseases,
- Decompensated heart failure,
- Chest deformity,
- Acute exacerbation within the last month,
- Pneumothorax,
- Body mass index greater than 35 kg/m²,
- Long-term corticosteroid use,
- Chemotherapy,
- Active malignancy,
- Inability to cooperate,
- Thoracoabdominal surgery within the last 3 months.
Key Trial Info
Start Date :
October 15 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 15 2027
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07193017
Start Date
October 15 2025
End Date
June 15 2027
Last Update
September 25 2025
Active Locations (1)
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1
Demiroglu Bilim University, Department of Physiotherapy and Rehabilitation
Istanbul, Turkey (Türkiye)