Status:
NOT_YET_RECRUITING
Impact of Chronic and Acute Caffeine Intake on the Hematopoietic System
Lead Sponsor:
Jasmin Rettkowski
Collaborating Sponsors:
ETH Zurich
Laboratory of Stem Cell Biology and Ageing, ETH Zurich, Prof. Nina Cabezas-Wallscheid
Conditions:
Healthy Adults; Hematopoietic System; Caffeine
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study investigates how caffeine intake affects blood stem and progenitor cells in healthy adults. The trial will compare people who regularly consume caffeine with those who consume very little ...
Eligibility Criteria
Inclusion
- Able to give consent.
- Healthy adults aged ≥ 18 years.
- Regular caffeine consumers (≥1 coffee cup/day or ≥1 energy drink/day) or non-consumers (≤1 cup/month and ≤1 energy drink/month) for at least 6 months.
- Willingness to comply with fasting requirements and study procedures.
Exclusion
- Chronic illnesses or medication use affecting metabolism, including metabolic disorders (e.g., diabetes, thyroid dysfunction, metabolic syndrome).
- Personal history of cancer.
- Personal history of hematological disorders.
- History of radiation therapy.
- Known caffeine hypersensitivity or intolerance.
- Known immunosuppression.
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2028
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT07193264
Start Date
October 1 2025
End Date
June 1 2028
Last Update
September 29 2025
Active Locations (1)
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1
ETH GLC
Zurich, Canton of Zurich, Switzerland, 8006