Status:
COMPLETED
Intra-Articular Polyacrylamide Hydrogel Injections Improve Pain and Function in Knee Osteoarthritis
Lead Sponsor:
Feza Korkusuz MD
Collaborating Sponsors:
Dr. Özgür Oktay Nar Private Clinic, Bursa, Türkiye
Contura International A/S, Copenhagen, Denmark
Conditions:
Knee Osteoarthritis
Osteoarthritis
Eligibility:
All Genders
40+ years
Brief Summary
This study is designed to evaluate the effects of intra-articular injections of polyacrylamide hydrogel (Arthrosamid®) in patients with knee osteoarthritis. A total of 387 patients (593 knees) were tr...
Eligibility Criteria
Inclusion
- Age ≥ 40 years
- Radiographic diagnosis of knee osteoarthritis (Kellgren-Lawrence grade 2-4)
- Received intra-articular 2.5% polyacrylamide hydrogel injection
Exclusion
- Prior knee surgery before PAAG injection
- Malignancy, local infection, or septic arthritis
- Inflammatory joint disease (e.g., rheumatoid arthritis)
- Pregnancy
- Avascular necrosis
- Advanced varus or valgus knee deformity
Key Trial Info
Start Date :
February 11 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 24 2025
Estimated Enrollment :
387 Patients enrolled
Trial Details
Trial ID
NCT07193368
Start Date
February 11 2023
End Date
June 24 2025
Last Update
September 25 2025
Active Locations (1)
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1
Hacettepe University, Faculty of Medicine, Department of Sports Medicine
Ankara, Turkey (Türkiye)