Status:

COMPLETED

Relationship Between Diabetes and Periodontitis

Lead Sponsor:

Afyonkarahisar Health Sciences University

Conditions:

Diabetes (DM)

Periodontitis

Eligibility:

All Genders

23-60 years

Brief Summary

Diabetes mellitus, one of the major global health problems of the 21st century, is a chronic metabolic disease characterized by dysregulated nutrient metabolism resulting from defects in insulin secre...

Detailed Description

Mechanisms by which diabetes mellitus affects the periodontium have been reported, including altering host immune, inflammatory, and wound-healing responses, promoting the accumulation of advanced gly...

Eligibility Criteria

Inclusion

  • Age between 20 and 65 years Diagnosed with Type 2 Diabetes Mellitus (T2DM) Diagnosed with periodontitis, according to established clinical criteria

Exclusion

  • Diagnosis of Type 1 Diabetes Mellitus Diagnosis of gestational diabetes Presence of physical or mental disorders that may affect participation or evaluation Undergoing chemotherapy or radiotherapy Presence of any systemic disease other than diabetes mellitus Use of systemic antibiotics or other medications in the past 3 months Use of antiparkinsonian, antidepressant, or antipsychotic medications

Key Trial Info

Start Date :

November 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2025

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT07193979

Start Date

November 1 2024

End Date

August 1 2025

Last Update

September 26 2025

Active Locations (1)

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Afyonkarahisar Health Sciences University Faculty of Dentistry

Afyonkarahisar, Turkey (Türkiye)