Status:
COMPLETED
One-Year Outcomes After Conventional vs Accelerated Epi-Off Corneal Cross-Linking in Progressive Keratoconus (Observational Cohort)
Lead Sponsor:
Clinical Hospital Centre Zagreb
Conditions:
Keratoconus
Eligibility:
All Genders
Brief Summary
Prospective, observational (consecutive eligible eyes) continuation of a previously published 6-month cohort from the same center, extending follow-up to 12 months. Patients with progressive keratocon...
Detailed Description
This prospective, single-center observational cohort extends the follow-up of a previously reported 6-month series from the same center to a 12-month horizon. The study population comprises consecutiv...
Eligibility Criteria
Inclusion
- Progressive keratoconus documented on serial Scheimpflug tomography within the prior 12 months (ABCD/K-metrics and/or pachymetry).
- Clear corneal axis (no visually significant scarring).
- Corneal thickness 370 μm or more
Exclusion
- No central corneal scars, prior chemical burns, severe corneal infection, or ocular surface disease.
- No pregnancy and lactation during treatment.
Key Trial Info
Start Date :
May 9 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 12 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT07194538
Start Date
May 9 2021
End Date
January 12 2023
Last Update
October 1 2025
Active Locations (1)
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1
University Hospital Centre Zagreb
Zagreb, Croatia, 10 000