Status:
ENROLLING_BY_INVITATION
Comparative Analysis of NTG-Pd/Pa and Saline-Pd/Pa (CANS)
Lead Sponsor:
National Taiwan University Hospital
Collaborating Sponsors:
Miaoli General Hospital, Ministry of Health and Welfare, Taiwan
Taichung Veterans General Hospital
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
21+ years
Brief Summary
The goal of this observational study is to compare the value of NTG-Pd/Pa and saline-Pd/Pa in participants with intermediate stenosis of the coronary artery. The main questions it aims to answer are: ...
Detailed Description
Fractional Flow Reserve (FFR) is the gold standard for determining the functional ischemia of coronary arteries with intermediate lesions. Both intracoronary nitroglycerine (NTG) administration and sa...
Eligibility Criteria
Inclusion
- Participants with coronary artery with 50-90% stenosis.
- In participants who suffered from ST elevation myocardial infarction within 5 days, only the non-culprit vessel was eligible for coronary functional testing.
Exclusion
- Systolic blood pressure is less than 90 mmHg for more than 5 minutes during examination.
- Resting heart rate is less than 50 beats per minute.
- Heart failure remains decompensated at the time of examination, such as inability to lie flat or cardiogenic shock.
- Acute onset of asthma or chronic obstructive pulmonary disease.
Key Trial Info
Start Date :
September 17 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2029
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT07195968
Start Date
September 17 2025
End Date
December 31 2029
Last Update
September 29 2025
Active Locations (3)
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1
National Taiwan University Hospital Hsin-Chu Hospital
Hsinchu, Select, Taiwan, 30047
2
Miaoli General Hospital, Ministry of Health and Welfare
Miaoli, Taiwan, 36054
3
Taichung Veterans General Hospital
Taichung, Taiwan, 407219