Status:
ACTIVE_NOT_RECRUITING
Comparison of Liposomal Bupivacaine Versus Ropivacaine in Alleviating Rebound Pain
Lead Sponsor:
Liu Jiuhong
Conditions:
Rebound Pain
Liposomal Bupivacaine
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
Shoulder arthroscopy is a frequently performed orthopedic procedure used to address various issues like rotator cuff tears, instability, and stiffness. However，postoperative pain is a common complaint...
Detailed Description
Shoulder arthroscopy represents a frequently employed orthopedic procedure for managing a wide spectrum of pathologic shoulder conditions, including rotator cuff tears, glenohumeral instability, and s...
Eligibility Criteria
Inclusion
- adults between 18 and 65 year-old
- American Society of Anesthesiologist (ASA) grades 1 to 3 physical classification status
- patients unilateral primary arthroscopic shoulder surgery lasting 1to 4 hours
Exclusion
- had an allergy or intolerance to amide-type local anesthetics
- objective evidence of nerve damage in the affected upper limb
- local infection
- impaired renal function (defined as effective glomerular filtration rate \< 30ml/min/1.73m2)
- coagulation disorders
- respiratory compromise（requires long term oxygen）
- had participated in another research trial involving an investigational medicinal product in the 6 months before randomization
Key Trial Info
Start Date :
September 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 5 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT07196631
Start Date
September 20 2025
End Date
February 5 2026
Last Update
December 16 2025
Active Locations (1)
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1
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030