Status:
NOT_YET_RECRUITING
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
Lead Sponsor:
Aga Khan University
Conditions:
Breast Cancer
Pain, Chronic
Eligibility:
FEMALE
18-75 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to is to compare the effectiveness of ultrasound-guided Pecs block with intravenous ketamine versus intravenous ketamine infusion alone in preventing Chronic Post-Su...
Eligibility Criteria
Inclusion
- Adult female patients with breast cancer aged between 18-75 years
- ASA (American Society of Anesthesia) physical status I, II, and III
- Patients scheduled for elective breast cancer surgery (Mastectomy with or without axillary clearance)
Exclusion
- Refusal to participate or withdrawal of informed consent
- Surgical procedures involving breast reconstruction with flaps or implants
- Patient scheduled for bilateral mastectomy
- Reoperation on the same side due to cancer recurrence
- Known allergy or contraindication to study drugs
- History of severe psychiatric illness (e.g., major depression, bipolar disorder, schizophrenia)
- Chronic opioid use, substance abuse, or opioid addiction
- Pre-existing chronic pain or neuropathic pain disorders
- Coagulopathy, anticoagulation therapy, or localized infection at the site of block
- Uncontrolled hypertension and ischemic heart disease
Key Trial Info
Start Date :
October 6 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2027
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT07197684
Start Date
October 6 2025
End Date
May 1 2027
Last Update
September 29 2025
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