Status:

NOT_YET_RECRUITING

Randomized, Double-blind Crossover Trial Comparing Low-GI Functional vs. Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Adults With Suboptimal Triglyceridemia

Lead Sponsor:

University of Bologna

Conditions:

Cardiovascular Prevention

Diabetes Prevention

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Low-glycemic index (GI) carbohydrates help prevent type 2 diabetes and cardiovascular disease by reducing postprandial glucose, insulin spikes, inflammation, and triglyceride synthesis. They improve w...

Detailed Description

The consumption of carbohydrates with a low glycemic index (GI) has emerged as a cornerstone in the dietary prevention of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). The glycemic...

Eligibility Criteria

Inclusion

  • Male or female aged ≥ 18 years
  • TG\>150 mg/dL
  • Subjects who have the capability to communicate and to comply with the study's requirements.
  • Subjects agree to participate in the study and having dated and signed the informed consent form.

Exclusion

  • Gluten hypersensitivity/Coeliac disease diagnosis
  • BMI\>30 kg/m2
  • Any preventive treatments (i.e. lipid-lowering drugs, antihypertensives) not stabilized in type and dose for at least 3 months
  • Any medical or surgical condition that would limit the patient adhesion to the study protocol.

Key Trial Info

Start Date :

October 30 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 29 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT07198789

Start Date

October 30 2025

End Date

May 29 2026

Last Update

September 30 2025

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