Status:
NOT_YET_RECRUITING
Clinical Evaluation of Local Calcitriol Delivery on Maxillary Canine Retraction
Lead Sponsor:
Al-Azhar University
Conditions:
Maxillary Canine Retraction
Local Calcitriol Delivery
Eligibility:
All Genders
13-35 years
Phase:
NA
Brief Summary
This study will evaluate the effect of locally applied Calcitriol on dental and skeletal changes during upper canine retraction. It is a split-mouth randomized clinical trial, where Calcitriol will be...
Detailed Description
Orthodontic tooth movement depends on bone remodeling. This study investigates if Calcitriol, the active form of vitamin D3, can affect this process when applied locally during upper canine retraction...
Eligibility Criteria
Inclusion
- Presence of class I malocclusion requiring bilateral extraction of the maxillary first premolars and subsequent canine retraction.
- Presence of class II malocclusion requiring bilateral extraction of the maxillary first premolars and subsequent canine retraction.
- Age range between 13 and 35 years to include both adolescent and adult patients suitable for orthodontic treatment.
- Presence of permanent dentition.
- Good oral hygiene.
Exclusion
- History of chronic systemic disease.
- Presence of active gingival or periodontal disease.
- Known allergy or hypersensitivity to vitamin D.
- Pregnancy or lactation.
- History of previous orthodontic treatment.
- Presence of craniofacial anomalies affecting bone physiology.
Key Trial Info
Start Date :
November 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT07200349
Start Date
November 1 2025
End Date
October 1 2026
Last Update
October 1 2025
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