Status:
ENROLLING_BY_INVITATION
The Relationship Between Mechanical Properties of Respiratory and Lower Extremity Muscles and Other Parameters in Multiple Sclerosis
Lead Sponsor:
Sanko University
Conditions:
Multiple Sclerosis
Breath Tests
Eligibility:
All Genders
18-50 years
Brief Summary
Multiple sclerosis (MS) is a chronic inflammatory disease characterised by deterioration in the mechanics of the lower extremities and respiratory muscles and a decrease in respiratory function. Fatig...
Detailed Description
Multiple sclerosis (MS) is a chronic inflammatory disease characterised by demyelination and axonal degeneration in the central nervous system, leading to various motor and sensory impairments. Sympto...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Having been diagnosed with MS according to the revised McDonald criteria followed at the Neurology Outpatient Clinic of Sanko University Hospital,
- Being between 18 and 50 years of age,
- Not having had an attack in the last 6 months,
- Having an EDSS score of 4.5 or below,
- To have given consent for the study.
- Exclusion Criteria:
- History of lower extremity surgery within the last 12 months,
- To have undergone physiotherapy within the last 6 months,
- Presence of current trauma or fracture involving the lower extremities,
- Presence of another neuro-musculoskeletal or pulmonary disease besides MS,
- Inability to cooperate with measurements and demonstrate compliance,
- Having received pulse steroid therapy or botulinum toxin/phenol injection within the last 6 months.
Exclusion
Key Trial Info
Start Date :
January 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2026
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT07202780
Start Date
January 1 2025
End Date
April 1 2026
Last Update
October 2 2025
Active Locations (1)
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1
Sanko University
Gaziantep, şehitkamil, Turkey (Türkiye), 27500