Status:

NOT_YET_RECRUITING

Effects of Oxaliplatin-Induced Peripheral Neuropathy on Hand Function, Grip Strength and Quality of Life in Colorectal Cancer Patients

Lead Sponsor:

Fenerbahce University

Collaborating Sponsors:

Acibadem University

Conditions:

Peripheral Neuropathy Due to Chemotherapy

Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients

Eligibility:

All Genders

20+ years

Brief Summary

The aim of this study is to investigate the effects of oxaliplatin-induced peripheral neuropathy on hand function, grip strength, and quality of life in colorectal cancer patients. Assessing the motor...

Detailed Description

Oxaliplatin is a chemotherapy drug frequently used in the treatment of colorectal cancers, the third most common type of cancer. However, oxaliplatin is associated with long-term neurotoxicity, the mo...

Eligibility Criteria

Inclusion

  • Receiving chemotherapy due to a diagnosis of locally advanced or metastatic colorectal cancer,
  • Having received at least 3 cycles of single or combined oxaliplatin-based chemotherapy,
  • Aged 20 years or older,
  • No speech or hearing impairments,
  • Voluntary participation in the study.

Exclusion

  • Development of peripheral neuropathy due to causes other than chemotherapy (e.g., tumor compression, nutritional disorders, infections, or major systemic diseases such as diabetes mellitus),
  • Presence of mental or cooperation problems.

Key Trial Info

Start Date :

September 24 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 24 2026

Estimated Enrollment :

84 Patients enrolled

Trial Details

Trial ID

NCT07203066

Start Date

September 24 2025

End Date

February 24 2026

Last Update

October 2 2025

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Effects of Oxaliplatin-Induced Peripheral Neuropathy on Hand Function, Grip Strength and Quality of Life in Colorectal Cancer Patients | DecenTrialz