Status:
RECRUITING
Evaluation of the Impact of an Alteration of NAD+ Metabolism on the Renal Prognosis of Patients Admitted to Intensive Care (NI-AKI)
Lead Sponsor:
Ramsay Générale de Santé
Conditions:
Acute Renal Insufficiency
NAD
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Among all patients admitted to intensive care, it is estimated that more than half of them are exposed during their stay to acute renal failure (ARF). Impacting the vital prognosis to short term, the ...
Eligibility Criteria
Inclusion
- Patient, male or female aged over 18,
- Patient admitted to intensive care for a reason with a high risk of ARI: shock, sepsis, cardio-circulatory arrest, post-operative unscheduled surgery, post-operative cardiac surgery,
- Patient with normal renal function on admission,
- Patient affiliated to or beneficiary of a social security scheme,
- Patient having been informed and having given his/her free, informed and written consent
Exclusion
- Minor patient,
- History of chronic kidney disease,
- History of kidney transplant,
- Admission for a reason with a low risk of ARI (neuroresuscitation, voluntary drug intoxication with anxiolytics - antidepressants - psychotropic drugs),
- Acute non-infectious respiratory failure, (scheduled surgery other than cardiac surgery)
- Patient hospitalized without consent,
- Patient in a period of exclusion due to another research still in progress at the time of inclusion,
- Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision,
- Pregnant, breastfeeding or parturient woman.
Key Trial Info
Start Date :
March 17 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 5 2025
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07203131
Start Date
March 17 2025
End Date
December 5 2025
Last Update
October 2 2025
Active Locations (1)
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1
Hôpital Privé de l'Ouest Parisien
Trappes, France, 78190