Status:
ACTIVE_NOT_RECRUITING
Microderm for Root Coverage Procedures
Lead Sponsor:
Ohio State University
Conditions:
Connective Tissue Graft
Gum Recession
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This randomized pilot study will compare Acellular Dermal Matrix (ADM) and a microsurfaced Acellular Dermal Matrix (mADM) for wound healing, root coverage, gum tissue coverage of the surgical site, bl...
Detailed Description
Advancements in Periodontal Surgery techniques and materials have continuously progressed to improve patient dental health. While the patient's own gum tissue from another site of the mouth as a graft...
Eligibility Criteria
Inclusion
- Participants 18+ years of age who require a tissue graft due to gum tissue recession.
Exclusion
- Current smokers or users of nicotine replacement products
- Patients with diabetes (HbA1c \> 5.6%)
- Pregnant or lactating women
- Surgical sites with previous soft tissue graft.
- Patients with a history of bisphosphonate therapy, radiotherapy in the head and neck region for malignancies, or chemotherapy for treatment of malignant tumors
- Patients who are taking anticoagulant and antiplatelet medications.
- Patients with contraindications, e.g., allergy, for any of the medications used in the study (benzocaine, lidocaine, chlorhexidine rinse, ibuprofen)
- Poor oral hygiene (PII \>2)
Key Trial Info
Start Date :
February 13 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT07203326
Start Date
February 13 2025
End Date
December 1 2026
Last Update
November 26 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Ohio State University College of Dentistry
Columbus, Ohio, United States, 43210