Status:
NOT_YET_RECRUITING
AI-Guided Left Bundle Branch Area Pacing
Lead Sponsor:
Mayo Clinic
Conditions:
Heart Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Age: 18 years or older.
- Left Ventricular Ejection Fraction (LVEF): \<50% within 6 months prior to enrollment.
- QRS Duration: Resting QRS duration ≥ 130 ms on ECG OR anticipated right ventricular pacing \> 40% OR device in place with right ventricular pacing \> 40% within 6 months prior to enrollment.
- Medical Therapy: Optimized on guideline-directed medical therapy for heart failure.
- AI-ECG probability of low LVEF: \>0.5
- Exclusion Criteria
- Age less than 18 years old
- Inability to follow-up
- Pregnancy
Exclusion
Key Trial Info
Start Date :
January 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2027
Estimated Enrollment :
224 Patients enrolled
Trial Details
Trial ID
NCT07206602
Start Date
January 1 2026
End Date
November 1 2027
Last Update
January 5 2026
Active Locations (1)
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1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905