Status:
RECRUITING
Arterial Stiffness as a Tool to Investigate Adherence in Resistant Hypertension
Lead Sponsor:
Institut National de la Santé Et de la Recherche Médicale, France
Collaborating Sponsors:
Medtronic
Conditions:
Resistant Hypertension
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
According to WHO estimates, worldwide, 1.28 billion adults between the age of 30-79 years have hypertension. Furthermore, only 1 in 5 people with hypertension have it under control. In approximately 1...
Eligibility Criteria
Inclusion
- Patients between 18-90 years of age in both sexes, diagnosed with resistant hypertension.
- \- Resistance Hypertension defined as -
- Blood pressure at consultation \> 140 and/or 90 mmHg and/or 24h-ABPM (Ambulatory Blood Pressure Assessment) and/or in Home blood pressure measurement (HBPM) \> 130 and/or 80 mmHg despite taking three or more different classes of antihypertensive drugs at optimal doses, including a diuretic, on the day of screening irrespective of the BP on the day of the visit.
- Any office BP, ABPM or HBPM values in patients taking four or more different classes of antihypertensive drugs at optimal doses, including a diuretic.
- Patients scheduled for arterial stiffness assessment as a part of routine treatment.
- Patients eligible or affiliated with a social security scheme.
- Patients who provide written informed consent for participation.
Exclusion
- \- Inability to express consent to the study
- Persons subject to a judicial safeguard measure, under guardianship or curatorship.
- Patients with skin lesions (severe eczema, wounds, etc.) on the chest or neck that do not allow the application of the protective skin film on the area of interest; Allergies to the adhesive film.
- Subjects not affiliated with social security or an equivalent scheme.
- Linguistic incapacity or psychic refusal to read the information.
- Diseases carrying out a life -expectancy \<1 year according to clinical judgment
- Pregnant women (because of physiological hemodynamic changes in BP and stiffness during pregnancy)
- Arrhythmias: current AC/FA, high degree BAV.
- Persons subject to a period of exclusion for another research
- Foreseen inability to attend scheduled visits
Key Trial Info
Start Date :
November 27 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 27 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07207226
Start Date
November 27 2024
End Date
March 27 2026
Last Update
October 3 2025
Active Locations (1)
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1
Hopital Georges pompidou
Paris, Île-de-France Region, France, 75015