Status:
RECRUITING
Electroacupuncture Treatment for Post-stroke Cognitive Impairment
Lead Sponsor:
Ruijie Ma
Collaborating Sponsors:
Second Affiliated Hospital, School of Medicine, Zhejiang University
The Third Affiliated hospital of Zhejiang Chinese Medical University
Conditions:
Post-Stroke Cognitive Impairment (PSCI)
Eligibility:
All Genders
35-80 years
Phase:
NA
Brief Summary
Stroke is a global public health issue, and it has become a leading cause of death and disability in China. With the rapid aging of the Chinese population, its incidence rate is continuously rising. A...
Eligibility Criteria
Inclusion
- Inclusion criteria
- According to the Western diagnostic criteria for vascular cognitive impairment outlined in the "Chinese Guidelines for the Diagnosis and Treatment of Vascular Cognitive Impairment (2024 Edition)" developed by the Vascular Cognitive Impairment Branch of the Chinese Stroke Society.
- Meets the traditional Chinese medicine diagnostic criteria for vascular cognitive impairment in the "Guidelines for Traditional Chinese Medicine Diagnosis and Treatment of Vascular Mild Cognitive Impairment (2024)";
- The Mini Mental State Examination (MMSE) score ranges from 12-24, while the Montreal Cognitive Assessment (MoCA) score is below 24; Having cognitive impairment but not reaching the level of severe dementia; The National Institutes of Health Stroke Scale (NIHSS) score is ≤ 8 points; The Early Dementia Screening Scale (Ascertain Dementia 8, AD-8) score is less than 2 points;
- Age between 35-80 years old;
- Have basic communication skills, with Mandarin as the main language (communication language is sufficient), and have at least one stable caregiver;
- Sign the informed consent form.
- Exclusion criteria
- Merge serious primary chronic diseases such as heart, liver, kidney, endocrine system, and hematopoietic system, as well as severe cardiovascular and cerebrovascular diseases;
- Skin diseases or scar constitution such as herpes and ulceration are easy to appear on the body surface, which is not suitable for acupuncture and moxibustion treatment;
- Not suitable for repetitive MRI examinations, such as claustrophobia, arterial aneurysm embolization, etc;
- Patients with cognitive impairment or other severe neurological or mental disorders prior to the onset of this illness, and unstable control;
- Patients identified by other clinical trial personnel as unsuitable for this study;
- Participated in clinical research on related diseases in the past 3 months;
Exclusion
Key Trial Info
Start Date :
October 5 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 30 2027
Estimated Enrollment :
340 Patients enrolled
Trial Details
Trial ID
NCT07208019
Start Date
October 5 2025
End Date
March 30 2027
Last Update
December 17 2025
Active Locations (5)
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1
Zhejiang Provincial Hospital of Traditional Chinese Medicine
Hangzhou, Zhejiang, China, 310006
2
Hangzhou Hospital of Traditional Chinese Medicine
Hangzhou, Zhejiang, China, 310007
3
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310009
4
The Third Affiliated Hospital of Zhejiang Chinese Medical University
Hangzhou, Zhejiang, China, 310053