Status:
NOT_YET_RECRUITING
Mechanistic Studies of Chronic COPD Using Single-Cell Sequencing and Single-Cell Spatial Transcriptomics
Lead Sponsor:
Tongji University
Conditions:
COPD
Eligibility:
All Genders
Brief Summary
This study is an ambispective cohort study, the sample from patients were from both previously stored and freshly collected . The objective of this study is to investigate the molecular pathological c...
Eligibility Criteria
Inclusion
- Receiving lung resection surgery at the hospital for any reason；
- Diagnosed with COPD according to the 2024 GOLD guidelines；
- Tissue samples that meet collection requirements and are either agreed to be collected or already preserved；
Exclusion
- Improper preservation of pathological specimens, refusal to consent to sample collection, or incomplete clinical information；
- Combined with other factors causing obstructive airflow limitation;
- Diagnosed with asthma according to the GINA 2023 guidelines and with a history of asthma exacerbations within the past year;
- Combined with Advanced lung cancer;
- Receiving systemic immunosuppressive medications such as anti-rejection drugs;
Key Trial Info
Start Date :
September 30 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07208123
Start Date
September 30 2025
End Date
December 31 2027
Last Update
October 6 2025
Active Locations (1)
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1
Renji Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China, 200444