Status:

COMPLETED

Clinical Study of Pretreatment PET/CT Parameters for Predicting the Efficacy of 125I Seed Implantation in the Treatment of Malignant Tumors

Lead Sponsor:

Jiangxi Provincial Cancer Hospital

Conditions:

Malignant Tumors

Eligibility:

All Genders

Brief Summary

This study aimed to determine if pre-treatment 18F-FDG PET/CT metabolic parameters could predict the effectiveness of 125I seed implantation for malignant tumors. In a retrospective analysis of 41 pat...

Detailed Description

Objective The purpose of the research is to assess the role of pretreatment 18F-FDG PET/CT parameters in predicting the efficacy of 125I seed implantation in the treatment of malignant tumors, in orde...

Eligibility Criteria

Inclusion

  • (1) Interval between PET/CT imaging and 125I seed implantation ≤4 weeks; (2)CT follow-up performed 4 months post-125I seed implantation; (3) Primary tumor pathologically or cytologically diagnosed as malignant; (4) Metastatic or recurrent lesions implanted with 125I confirmed by cytological aspiration or imaging

Exclusion

  • (1) Lesions too small or SUVmax \< 2.5, rendering them unidentifiable by software for PET/CT parameter measurement; (2) Two 125I seed implantation procedures performed within 6 months for the same lesion; (3) Incomplete clinical or imaging data.

Key Trial Info

Start Date :

January 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2024

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT07208487

Start Date

January 1 2019

End Date

December 1 2024

Last Update

October 6 2025

Active Locations (1)

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Jiangxi Cancer Hospital

Nanchang, Jiangxi, China