Status:
NOT_YET_RECRUITING
Investigating Proprioceptive Impairment in Adolescents With Idiopathic Scoliosis (AIS) (SCOLIO-PROPRIO)
Lead Sponsor:
Assistance Publique Hopitaux De Marseille
Conditions:
Scoliosis Idiopathic Adolescent
Eligibility:
All Genders
10-18 years
Phase:
NA
Brief Summary
The goal of this interventionnal study is to learn if teenagers who have severe scoliosis (a curvature of the spine) have trouble sensing their body's position in space (this sense is called proprioce...
Detailed Description
Adolescent Idiopathic Scoliosis (AIS) affects 2 to 4% of the pediatric population. While its exact etiology remains unclear, one leading hypothesis implicates deficits in muscle proprioception, though...
Eligibility Criteria
Inclusion
- Adolescents diagnosed with Adolescent Idiopathic Scoliosis (AIS) and followed in the pediatric orthopedic surgery department, scheduled to undergo spinal fusion surgery (arthrodesis)
- No history or clinical signs of neurological disorders
- Aged between 10 and 18 years
- Written informed consent obtained from both the adolescent and their legal guardians (parents)
- Control Group only: Participants will be selected from open-access neuroimaging databases, matched to the patient group by age and sex.
Exclusion
- Presence of any other clinically significant condition that could be associated with spinal deformity
- Insufficient proficiency in French to understand the informed consent form
- Current treatment with psychotropic medication
- Ongoing pregnancy or breastfeeding
- Subject under legal or judicial supervision
- Contraindications to brain MRI (including: pacemaker; electrically, magnetically, or mechanically activated implants; surgical clips; metallic sutures; staples; etc. - see MRI safety questionnaire annex)
- Subject or their parent(s)/legal guardian(s) refuse to be informed of incidental findings detected during MRI
- Claustrophobia
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07208929
Start Date
October 1 2025
End Date
December 1 2027
Last Update
October 6 2025
Active Locations (1)
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1
Assistance Publique Hôpitaux de Marseille
Marseille, France, 13354