Status:

NOT_YET_RECRUITING

European LUpuS Inception-Cohort Developing initiATivE

Lead Sponsor:

University of Aarhus

Conditions:

Systemic Lupus Erythematosus (SLE)

Eligibility:

All Genders

16+ years

Brief Summary

The goal of this observational study is to learn more about how systemic lupus erythematosus (SLE or lupus) develops in the first years after diagnosis, and how patients respond to different treatment...

Detailed Description

PROTOCOL SYNOPSIS 1. Introduction Systemic lupus erythematosus (SLE) is a complex autoimmune disease with diverse clinical manifestations. Despite recent therapeutic advances, challenges persist, inc...

Eligibility Criteria

Inclusion

  • Inclusion at clinical diagnosis of SLE (or strong clinical suspicion hereof) before initiating treatment (if treatment has been initiated, patients can still be included if it is less than six months since diagnosis and the patient has clinically and biochemically active disease (SLEDAI\>6).
  • Fulfilling the 2019 ACR/EULAR criteria for Systemic Lupus Erythematosus
  • \>18 years of age (adult onset SLE)
  • Ability to provide informed voluntary consent.

Exclusion

  • Diagnosed with overlapping systemic autoimmune diseases other than secondary Sjögren's syndrome or antiphospholipid syndrome.
  • Active treatment for malignancy at the time of enrolment, except for non-melanoma skin cancer or localized carcinoma in situ of the skin.

Key Trial Info

Start Date :

July 1 2026

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2033

Estimated Enrollment :

700 Patients enrolled

Trial Details

Trial ID

NCT07209540

Start Date

July 1 2026

End Date

July 1 2033

Last Update

October 7 2025

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European LUpuS Inception-Cohort Developing initiATivE | DecenTrialz