Status:

RECRUITING

AK+ Guard™ Pilot Study in Chronic Kidney Disease: Outpatient Diagnostic Accuracy and Remote Monitoring

Lead Sponsor:

AccurKardia, Inc.

Conditions:

Hyperkalemia

Chronic Kidney Disease (Stage 3-4)

Eligibility:

All Genders

22+ years

Brief Summary

The goal of this observational pilot study is to evaluate the investigational AK+ Guard™ software as a medical device (SaMD) for detection of moderate to severe hyperkalemia (serum potassium (K+) ≥ 6....

Detailed Description

The AK+ Guard™ application is an investigational Software as a Medical Device (SaMD) developed by AccurKardia, Inc. (New York, USA). It is designed to aid in the diagnosis of moderate to severe hyperk...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • (Arm 2A - Outpatient Diagnostic Accuracy)
  • Age 22 years or older
  • CKD stages III-IV managed at Central Jersey Kidney Care outpatient clinic
  • Scheduled outpatient serum potassium laboratory test
  • On RAASi therapy or documented hyperkalemia (K+ ≥ 5.5 mmol/L) within the past 12 months
  • Able to provide written informed consent
  • (Arm 2B - Remote Patient Monitoring)
  • Completion of Arm 2A visit
  • Owns an iPhone compatible with the study application
  • Exclusion Criteria (Both arms):
  • Age 21 years or younger
  • Pacemaker or implantable cardioverter defibrillator
  • Pre existing Left Bundle Branch Block (LBBB), Right Bundle Branch Block (RBBB), Intraventricular Conduction Delay (IVCD), or clinically significant hypocalcemia
  • Potassium lowering treatment administered before Lead I ECG acquisition
  • Trauma, acute events, or active interventions altering potassium homeostasis
  • Physical limitation precluding ECG acquisition

Exclusion

    Key Trial Info

    Start Date :

    October 14 2025

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    November 28 2025

    Estimated Enrollment :

    50 Patients enrolled

    Trial Details

    Trial ID

    NCT07210021

    Start Date

    October 14 2025

    End Date

    November 28 2025

    Last Update

    October 16 2025

    Active Locations (1)

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    Central Jersey Kidney Care - Hypertension & Nephrology Associates

    Eatontown, New Jersey, United States, 07724