Status:
RECRUITING
Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI
Lead Sponsor:
Mayo Clinic
Collaborating Sponsors:
The Craig H. Neilsen Foundation
Conditions:
Spinal Cord Injuries
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The purpose of this research is to learn about how the body is able to balance changes in blood pressure, how that changes over time, and how these changes impact a participant's risk of developing me...
Eligibility Criteria
Inclusion
- Inclusion criteria
- 18-75 years old
- Spinal cord injury with neurological level of injury from C6-T12
- ASIA Impairment Scale A-D.
- Either acute SCI \<3 months prior (n=10) or chronic SCI (\>1 year since injury, n=8).
- Exclusion criteria
- Symptoms of cardiovascular (including, but not limited to: hypertension, stroke, chest pain, etc.), respiratory, peripheral neurological or autonomic disease (particularly diabetes mellitus requiring treatment);
- Women who are pregnant or lactating
- Taking or being administered a medication known to potentially have adverse interactions with phenylephrine
- In the judgement of the principal investigator, any illness or condition that will interfere with the patient's ability to comply with the protocol, compromise patient safety, or interfere with the interpretation of the study results.
Exclusion
Key Trial Info
Start Date :
February 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2028
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT07210437
Start Date
February 1 2026
End Date
June 1 2028
Last Update
December 15 2025
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905