Status:

NOT_YET_RECRUITING

Activity of Mouthwashes Againgst Entamoeba Spp.

Lead Sponsor:

Medical University of Vienna

Conditions:

Parasite Infestation

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The amoeba Entamoeba gingivalis colonizes the human oral cavity, where it can actively destroy tissue and cause local inflammation. Currently, there is no standard treatment for E. gingivalis infectio...

Eligibility Criteria

Inclusion

  • Adults aged 18 years or older
  • Able and willing to provide written informed consent
  • Positive identification of Entamoeba gingivalis in oral samples collected during screening, confirmed by specific PCR

Exclusion

  • Antibiotic therapy or periodontal treatment within the last 6 months
  • Current orthodontic treatment
  • Underlying systemic diseases (e.g., diabetes mellitus)
  • Autoimmune diseases
  • Acute infections and other conditions requiring medication
  • Pregnancy

Key Trial Info

Start Date :

October 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT07210814

Start Date

October 1 2025

End Date

March 1 2026

Last Update

October 7 2025

Active Locations (1)

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1

Institute for Specific Prophylaxis and Tropical Medicine

Vienna, Austria, 1090