Status:

COMPLETED

Serum Trace Element Levels in Some Gynecological Diseases

Lead Sponsor:

Cumhuriyet University

Conditions:

Endometriosis

Endometrial Cancer

Eligibility:

FEMALE

18-55 years

Phase:

NA

Brief Summary

The aim of this clinical study is to measure the levels of various trace elements in the blood serum of women with various gynecological diseases and to compare them with healthy controls. The main qu...

Detailed Description

However, the serum trace elements profiles of individuals with endometriosis, ovarian cancer (OC), and endometrial cancer (EC) are not fully known. The purpose of this study is to examine the levels o...

Eligibility Criteria

Inclusion

  • Not having received chemotherapy, radiotherapy or immunotherapy in the last three months
  • For the endometriosis group: histopathologically or laparoscopically confirmed endometriosis
  • For the ovarian cancer group: histopathologically confirmed epithelial ovarian cancer
  • For the endometrial cancer group: histopathologically confirmed endometrial adenocarcinoma
  • For the control group: healthy individuals who underwent surgery for benign gynecological causes (e.g., myoma, benign cyst) and who were not diagnosed with malignancy/endometriosis

Exclusion

  • Chronic systemic diseases (e.g., chronic renal failure, liver disease, severe cardiac disease)
  • Diseases that may affect metabolism or trace element levels (e.g., Wilson's disease, hemochromatosis)
  • Use of dietary supplements containing minerals or trace elements within the past 6 months
  • Environmental or occupational heavy metal exposure (e.g., mining, metallurgy, battery industry workers)
  • Pregnancy or breastfeeding
  • History of acute infection or inflammatory disease
  • History of recurrent surgery or advanced metastatic cancer (as this may alter serum parameters)
  • Psychiatric or cognitive disorders that preclude participation in the study

Key Trial Info

Start Date :

April 24 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 29 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT07210918

Start Date

April 24 2025

End Date

September 29 2025

Last Update

November 24 2025

Active Locations (1)

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sivas Cumhuriyet University

Sivas, Centre, Turkey (Türkiye), 58146

Serum Trace Element Levels in Some Gynecological Diseases | DecenTrialz