Status:

NOT_YET_RECRUITING

Comparison Of Cytology And Molecular Screening For Detecting Cervical Reactive Cellular Changes In General Population

Lead Sponsor:

Timser SAPI de CV

Conditions:

Atypical Squamous Cell of Undetermined Significance

ASC-US

Eligibility:

FEMALE

18-85 years

Phase:

NA

Brief Summary

This study compares the efficacy of cytology (Pap smear) with the molecular screening in their ability to detect reactive cellular changes in the cervix among an open population

Detailed Description

The primary goal of this study is to compare the efficacy of the cytology (Pap smear) with the molecular screening -of three human biomarkers- in their ability to detect reactive cellular changes in t...

Eligibility Criteria

Inclusion

  • Be in good general health.
  • Age 18-85 years.
  • A minimum fast of 6 hours and no more than 12 hours.
  • Refrain from sexual intercourse 24 hours before the study.
  • Give written informed consent.

Exclusion

  • Having a subtotal, total, or radical hysterectomy.
  • Being pregnant or suspected of being pregnant. A rapid urine test will be performed. If the result is positive, the patient will be excluded from the protocol and referred for prenatal care.
  • Being under oncological treatment (chemotherapy, radiotherapy and/or brachytherapy).
  • Being on their period.
  • Have a previous confirmatory diagnosis of HIV and/or hepatitis infection.
  • Having taken antiplatelet medications, e.g., acetylsalicylic acid, at least 24 hours before the study.
  • Discontinuation Criteria:
  • If the participant refuses any of the study procedures.
  • If the study gynecologist detects that the participant has had a hysterectomy.
  • If the volume of the biological samples is insufficient (less than 10 mL for the blood sample).

Key Trial Info

Start Date :

November 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT07211204

Start Date

November 1 2025

End Date

September 1 2026

Last Update

October 7 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Clinica Reina Madre Metepec

San Mateo Atenco, State of Mexico, Mexico, 52105

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