Status:
NOT_YET_RECRUITING
Dosimetric Differences and Clinical Significance Analysis Between Body Gamma Knife and VMAT Radiotherapy for Primary Liver Cance
Lead Sponsor:
Chifeng Tumor Hospital
Conditions:
Primary Liver Cancers
Eligibility:
All Genders
18-75 years
Brief Summary
To fill in the "Brief Summary" field, you need to provide clear, easy-to-understand information about the study for patients, families, and healthcare providers. Here's a suggested summary: This stud...
Eligibility Criteria
Inclusion
- Aged 18-75 years.
- Clinically or pathologically confirmed primary liver cancer; unsuitable for or - refusing surgery, with single tumor diameter ≤5 cm and ≤5 nodules.
- ECOG PS score 0-1.
- Liver function: Child-Pugh grade A or B.
- Prothrombin time (PT) \< 4 seconds above the normal control range.
- No hepatic encephalopathy or moderate to large ascites.
- Renal and cardiopulmonary function basically normal.
- Gastroscopy findings: no severe esophageal varices or active peptic ulcer.
- Hemoglobin ≥90 g/L, WBC ≥3.0×10⁹/L, neutrophil ≥1.5×10⁹/L, platelet ≥40×10⁹/L.
- No obvious cachexia; life expectancy \> 3 months.
- Not pregnant; no HIV or syphilis infection.
- Able to understand the study and sign informed consent.
Exclusion
- History of portal hypertension, esophageal variceal bleeding, or related conditions.
- History of anti-RHCC treatment or spontaneous tumor rupture.
- Postoperative pathology indicates metastatic cancer or other primary cancers.
- Cerebrovascular accident within 6 months before enrollment.
- Severe lung disease; serum creatinine \> 1.25×the upper normal limit.
- Poorly controlled acute or active infection; severe mental illness.
- Suspected systemic or local lymphadenopathy on imaging.
- Pregnant or lactating women; presence of other serious underlying diseases.
- Currently participating in other clinical trials; refusal to provide informed consent.
Key Trial Info
Start Date :
November 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07211815
Start Date
November 1 2025
End Date
June 1 2027
Last Update
October 8 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chifeng Tumor Hospital
Chifeng, Inner Mongolia, China, 024000