Status:

RECRUITING

Collection of Stool From Healthy Donors for the ex Vivo Study of Shifts of Microbiome Induced by Dairy Phages and Antibiotics: a Model of Bacteria/Host Interaction (DAIRY-SHAPE)

Lead Sponsor:

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Conditions:

General Population (no Specific Condition or Disease)

Eligibility:

All Genders

18-60 years

Brief Summary

The gut microbiota plays a crucial role in health through its involvement in pathogen defense, immune regulation, and nutrient digestion. Microbiota diversity is essential to maintain these functions,...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years and ≤ 60 years
  • Varied and balanced omnivorous diet

Exclusion

  • Vegetarian, vegan, or restrictive diet
  • Use of medications (antibiotics, anti-inflammatory drugs, immunosuppressants, and/or probiotics, prebiotics, or synbiotics), either as drugs or dietary supplements, within the 3 months prior to sample collection
  • Pregnant and/or breastfeeding women
  • Presence of an acute or chronic disease (gastrointestinal, metabolic, immune, or inflammatory), diagnosed or suspected
  • Colonoscopy within the past 3 months
  • Known food allergy or intolerance (e.g., gluten, lactose, FODMAPs) that may alter the usual diet and/or microbiota composition
  • Individuals under legal protection (guardianship, trusteeship, etc.)

Key Trial Info

Start Date :

October 16 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 16 2028

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT07212400

Start Date

October 16 2025

End Date

November 16 2028

Last Update

November 19 2025

Active Locations (1)

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Metagenopolis

Jouy-en-Josas, France, 78352