Status:
COMPLETED
Methylene Blue-Enhanced Ultrafiltration Improves Outcomes After Cardiopulmonary Bypass
Lead Sponsor:
University of Sao Paulo
Conditions:
Cardiopulmonary Bypass Surgery
Aortic Valve Surgery
Eligibility:
All Genders
20-60 years
Phase:
PHASE2
Brief Summary
Introduction: Fluid overload and systemic inflammation are major contributors to postoperative complications in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Objective: To eva...
Eligibility Criteria
Inclusion
- Clinical diagnosis of cardiac disease requiring surgery with cardiopulmonary bypass (CPB)
- Age ≥ 18 years
- Ability to provide informed consent
Exclusion
- Chronic renal failure
- Recent cardiac catheterization within the past month
- Planned cardiac surgeries with an estimated CPB time of less than 60 minutes
- Aortic surgery
- Significantly impaired hepatic function
Key Trial Info
Start Date :
April 12 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 16 2024
Estimated Enrollment :
124 Patients enrolled
Trial Details
Trial ID
NCT07212842
Start Date
April 12 2021
End Date
March 16 2024
Last Update
October 8 2025
Active Locations (1)
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1
University of São Paulo Medical School in Ribeirão Preto
Ribeirão Preto, São Paulo, Brazil, 14049-900