Status:

RECRUITING

Metabolic Effects of Short-term Ultra-processed Food Intake (MEST-UPF)

Lead Sponsor:

Göteborg University

Conditions:

Appetite

Obesity and Obesity-related Medical Conditions

Eligibility:

All Genders

18-50 years

Phase:

NA

Brief Summary

The overall aim of this project is to study the effects of short-term high ultra-processed food intake, compared to nutrient- and energy density matched low ultra-processed food (UPF) intake, on energ...

Eligibility Criteria

Inclusion

  • Body mass index (BMI) 18.5-30 kg/m2
  • Fasting glucose \< 6.1 mmol/l
  • Hb \>110 g/L
  • Weight stability the last 3 months +/-5%

Exclusion

  • Food allergies, intolerances or preferences preventing consumption of any products included in the study.
  • Unable to sufficiently understand written and spoken Swedish or English to provide written consent and understand information and instructions from the study personal.
  • Pregnant, lactating or planning a pregnancy during the study period.
  • Blood donation or participation in a clinical study with blood sampling within 30 days prior to screening visit and throughout the study.
  • History of gastrointestinal conditions or major gastrointestinal surgery (Inflammatory bowel disease, Crohn's disease, malabsorption, colostomy, bowel resection, gastric bypass surgery etc.).
  • Type 1 diabetes or type 2 diabetes.
  • Thyroid disorder.
  • Current smoking, vaping.
  • Following any weight reduction program or having followed one during the last 6 months prior to screening.
  • Not habitually eating breakfast (\<5 times/week).
  • Restrained eating based on the three-factor eating questionnaire.

Key Trial Info

Start Date :

December 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2026

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT07213245

Start Date

December 1 2025

End Date

April 30 2026

Last Update

December 15 2025

Active Locations (1)

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1

Department of internal medicine and clinical nutrition, University olf Gothenburg

Gothenburg, Sweden, 40530