Status:
NOT_YET_RECRUITING
Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease
Lead Sponsor:
Hospital de Clinicas de Porto Alegre
Conditions:
Parkinsons Disease (PD)
Constipation - Functional
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD). The main questions it aims...
Eligibility Criteria
Inclusion
- Adults with a previous diagnosis of Parkinson's disease
- On a stable dose of levodopa for at least 3 months
- Diagnosis of Functional Constipation by the Rome IV protocol
Exclusion
- Diagnosis of atypical or secondary parkinsonism
- Hoehn and Yahr stage greater than 2
- Presence of severe neurological or psychiatric disorders that impair the ability to participate in study procedures
- Previous diagnosis of dementia
- Presence of comorbidities such as active cancer, chronic obstructive pulmonary disease (COPD), heart failure, and/or chronic kidney disease
- History of gastrointestinal cancers, inflammatory bowel diseases, or surgeries involving the gastrointestinal tract
- Constipation secondary to clinical conditions such as hypothyroidism or diabetes mellitus
- Use of opioids
- Use of probiotics or antibiotics in the past 8 weeks
- Continuous use of laxatives in the past 8 weeks
- Presence of severe dysphagia according to the Functional Oral Intake Scale (FOIS)
- Individuals receiving enteral or parenteral nutrition
- Individuals under nutritional follow-up in the past 3 months
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2029
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT07213856
Start Date
October 1 2025
End Date
August 1 2029
Last Update
October 9 2025
Active Locations (1)
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1
Hospital de Clínicas de Porto Alegre (HCPA)
Porto Alegre, Rio Grande do Sul, Brazil