Status:
COMPLETED
Novel DBS Device in Parkinson's Disease
Lead Sponsor:
University of Minnesota
Collaborating Sponsors:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Parkinson's Disease (PD)
Eligibility:
All Genders
22-75 years
Phase:
NA
Brief Summary
The purpose of this research is to test a new recorder that can measure brain activity when stimulation is turned on during deep brain stimulation (DBS) surgery. To continue to improve DBS therapy, th...
Detailed Description
Deep brain stimulation (DBS) is shown to be very effective in alleviating the motor symptoms of Parkinson's disease (PD). However, its exact mechanism is not well-understood. Clinical studies have rep...
Eligibility Criteria
Inclusion
- Has unilateral STN or GPi DBS and is approved to undergo second or contralateral side implantation;
- Diagnosis of idiopathic PD;
- A history of a good response to levodopa (carbidopa/levodopa) defined as at least a 30% improvement in motor unified Parkinson's disease rating scale (UPDRS) score;
- DBS surgery at UMN is planned as part of routine clinical care.
Exclusion
- Other significant neurological disorder
- History of dementia
- Patients with post-operative complications or adverse effects (e.g. ON stimulation dystonias) that affect patient safety or confound the experiment will be excluded from further study
- Pregnant women
Key Trial Info
Start Date :
July 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 2 2022
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT07213999
Start Date
July 1 2022
End Date
July 2 2022
Last Update
October 9 2025
Active Locations (1)
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1
University of Minnesota Medical Center
Minneapolis, Minnesota, United States, 55455