Status:
NOT_YET_RECRUITING
Vagus Nerve Stimulation to Enhance Memory in Aging
Lead Sponsor:
Stanford University
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Alzheimer Disease
Aging
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The aim of this study is to determine whether non-invasive vagus nerve stimulation enhances memory formation in cognitively healthy older adults and whether the effects of stimulation depend on gut an...
Eligibility Criteria
Inclusion
- Ages 18-30 years or 65-80 years
- Normal or corrected-to-normal vision (visual acuity)
- Fluent in English
Exclusion
- Pregnant
- Symptoms of memory loss
- History of a neurological, psychiatric, or medical condition that could affect cognition or preclude MRI or pupillometry
- Use of medications known to alter cognition
- For older adults, neuropsychological performance that falls outside 1.5 standard deviations of age-adjusted norms and no self-reported memory or attention complaints
Key Trial Info
Start Date :
February 1 2027
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2028
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07214194
Start Date
February 1 2027
End Date
July 1 2028
Last Update
October 9 2025
Active Locations (1)
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1
Stanford University
Stanford, California, United States, 94305