Status:

NOT_YET_RECRUITING

Neuropsychiatric Outcomes and Disrupted Sleep Following Acquired Brain Injury

Lead Sponsor:

University of Oxford

Conditions:

Acquired Brain Injury (Including Stroke)

Eligibility:

All Genders

18+ years

Brief Summary

The two most common causes of brain injury are stroke and trauma. Both sleep and mental health problems are common after brain injury; we will investigate whether there is a relationship between poor ...

Detailed Description

This is a cross-sectional and longitudinal observational cohort study to assess the relationship between sleep quality and neuropsychiatric symptoms in adults within 12 months of an acquired brain inj...

Eligibility Criteria

Inclusion

  • Willing and able to give informed consent for participation in the study.
  • Aged 18 years or above.
  • At least one week, but less than 12 months post-injury
  • Clinical diagnosis of acquired brain injury (stroke, haemorrhage or traumatic).
  • Participants with Traumatic Brain Injury will have a Mild (probable) or Moderate-severe (definite) brain injury according to the Mayo classification
  • Participants must be willing to consent to us contacting their general practitioner (GP) or direct care team if we have concerns about their mental health

Exclusion

  • Brain injury not caused by trauma, haemorrhage or stroke
  • Previous brain injury.
  • Other relevant neurological conditions which could affect outcome measures (e.g., Parkinson's or Alzheimer's disease)
  • No stable and suitable place to sleep

Key Trial Info

Start Date :

October 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 30 2027

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT07215195

Start Date

October 1 2025

End Date

November 30 2027

Last Update

October 10 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Wellcome Centre for Integrative Neuroimaging (WIN) FMRIB, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford OX3 9DU

Oxford, United Kingdom, OX3 9DU