Status:
RECRUITING
Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.1
Lead Sponsor:
Indiana University
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Healthy Volunteers
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
In its totality, this grant aims to develop a line of research using temporal interference (TI) electrical neurostimulation technology to understand the causal role of deep brain structures in cogniti...
Detailed Description
Through the grant's duration, the investigators hypothesize that temporal interference (TI) electrical neurostimulation will be well tolerated and effective at focally manipulating deep brain activity...
Eligibility Criteria
Inclusion
- Between the ages of 18 and 50
- Must have at least a 6th grade education
- Ability to speak and read English for all phases
Exclusion
- Currently taking psychotropic medications for ADHD, other mental illness, or medications for cancer
- History of epilepsy or seizure disorders
- History of migraines or other neurological syndromes
- History of AIDS (due to potential cognitive deficits)
- History of head trauma or cognitive impairments
- Personal experiences consistent with symptoms of psychosis (e.g., hallucinations, delusions of control or special powers)
- History of skull defects (e.g., holes bored into the skull or known cranial fissures)
- Metal implants in the head or under the scalp
- Does not meet fMRI safety screening criteria (e.g., metal implants in the body, permanent jewelry, tattoos on the head or neck)
- Uses an intrauterine device (IUD) for birth control and cannot provide documentation to verify MRI safety
- Pregnancy (self-reported; no pregnancy test administered)
- Weight over 440 lbs (scanner weight limit)
- Presence of pacemakers
Key Trial Info
Start Date :
November 12 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 21 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07215299
Start Date
November 12 2025
End Date
January 21 2026
Last Update
January 7 2026
Active Locations (1)
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1
Indiana University Bloomington, Imaging Research Facility
Bloomington, Indiana, United States, 47408