Status:

COMPLETED

Characterization and Clinical Outcomes of Severe Asthma Patients in Israel Treated With Benralizumab (SAIL-B)

Lead Sponsor:

AstraZeneca

Conditions:

Severe Asthma

Eligibility:

All Genders

Brief Summary

A retrospective, observational, one arm, single country study, using the computerized database of Maccabi Health Services (MHS). The study will include adult patients who initiated benralizumab treatm...

Eligibility Criteria

Inclusion

  • An authorization from MHS drugs authorization center for benralizumab, with a diagnosis of asthma (ICD-9 code 493.X and the corresponding internal MHS diagnosis codes for SA). Having an authorization indicates that patients have severe eosinophilic asthma and fulfil the GINA definition of severe asthma as well as additional local reimbursement criteria.
  • At least one purchase of benralizumab for the first time between January 1 2019 and March 31 2024.
  • Age ≥18 years on the index date.
  • MHS members for at least 12 months before the index date.

Exclusion

  • • Patients who received benralizumab for indication other than asthma according to MHS drugs authorization center.
  • \- currently or recently included in a clinical trial according to the ICD-9 diagnosis code V70.7) and the corresponding internal MHS codes

Key Trial Info

Start Date :

March 24 2025

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 24 2025

Estimated Enrollment :

197 Patients enrolled

Trial Details

Trial ID

NCT07218172

Start Date

March 24 2025

End Date

April 24 2025

Last Update

October 17 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Research Site

Tel Aviv, Israel